Radiosensitization and Radioprotection by Curcumin in Glioblastoma and Other Cancers

Radiosensitization and Radioprotection by Curcumin in Glioblastoma and Other Cancers

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Radiation therapy plays an important role in almost every cancer treatment.However, radiation toxicity to normal tissues, mainly due to the generation of reactive free radicals, has limited the efficacy of radiotherapy in clinical practice.Curcumin has been reported to possess significant antitumor properties.

Although curcumin can sensitize cancer hanes 42tb cells to irradiation, healthy cells are much less sensitive to this effect, and thus, curcumin is thought to be a potent, yet safe anti-cancer agent.In this review, a summary of the role of curcumin as both a radiosensitizer yamaha c115v specs and radioprotector has been presented, based on the most recent data from the experimental and clinical evaluation of curcumin in different cancer cell lines, animal models, and human patients.